Machine Learning Operations (MLOps) practices are increas- ingly adopted in industrial settings, yet their integration with Opera- tional Technology (OT) systems presents significant challenges. This pa- per analyzes the fundamental obstacles in combining MLOps with OT en- vironments and proposes a systematic approach to embed MLOps prac- tices into established OT reference models. We evaluate the suitability of the Reference Architectural Model for Industry 4.0 (RAMI 4.0) and the International Society of Automation Standard 95 (ISA-95) for MLOps integration and present a detailed mapping of MLOps lifecycle compo- nents to RAMI 4.0 exemplified by a real-world use case. Our findings demonstrate that while standard MLOps practices cannot be directly transplanted to OT environments, structured adaptation using existing reference models can provide a pathway for successful integration.

The seamless integration of physical and digital environments in Cyber-Physical Systems(CPS), particularly within Industry 4.0, presents significant challenges stemming from system heterogeneity and complexity. Traditional approaches often rely on rigid, data-centric solutions like co-simulation frameworks or brittle point-to-point middleware bridges, which lack the semantic richness and flexibility required for intelligent, autonomous coordination. This report introduces the Knowledge Graph-Enhanced Multi-Agent Infrastructure(KG-MAS), as resolution in addressing such limitations. KG-MAS leverages a centralized Knowledge Graph (KG) as a dynamic, shared world model, providing a common semantic foundation for a Multi-Agent System(MAS). Autonomous agents, representing both physical and digital components, query this KG for decision-making and update it with real-time state information. The infrastructure features a model-driven architecture which facilitates the automatic generation of agents from semantic descriptions, thereby simplifying system extension and maintenance. By abstracting away underlying communication protocols and providing a unified, intelligent coordination mechanism, KG-MAS offers a robust, scalable, and flexible solution for coupling heterogeneous physical and digital robotic environments.

To achieve a highly agile and flexible production, it is envisioned that industrial production systems gradually become more decentralized, interconnected, and intelligent. Within this vision, production assets collaborate with each other, exhibiting a high degree of autonomy. Furthermore, knowledge about individual production assets is readily available throughout their entire life-cycles. To realize this vision, adequate use of information technology is required. Two commonly applied software paradigms in this context are Software Agents (referred to as Agents) and Digital Twins (DTs). This work presents a systematic comparison of Agents and DTs in industrial applications. The goal of the study is to determine the differences, similarities, and potential synergies between the two paradigms. The comparison is based on the purposes for which Agents and DTs are applied, the properties and capabilities exhibited by these software paradigms, and how they can be allocated within the Reference Architecture Model Industry 4.0. The comparison reveals that Agents are commonly employed in the collaborative planning and execution of production processes, while DTs typically play a more passive role in monitoring production resources and processing information. Although these observations imply characteristic sets of capabilities and properties for both Agents and DTs, a clear and definitive distinction between the two paradigms cannot be made. Instead, the analysis indicates that production assets utilizing a combination of Agents and DTs would demonstrate high degrees of intelligence, autonomy, sociability, and fidelity. To achieve this, further standardization is required, particularly in the field of DTs.